The EMD Polyclonal Antibody (CAB13925) is a high-quality antibody designed for researchers studying EMD, a transmembrane protein associated with cell adhesion and migration. The antibody is produced in rabbits and has been validated for use in various applications, including Western blot analysis. It specifically binds to the EMD protein, allowing for accurate detection and analysis in a variety of cell types.EMD, also known as Emerin, plays a significant role in maintaining the integrity of the nuclear envelope and is implicated in the regulation of gene expression and signal transduction. Dysregulation of EMD has been linked to a range of diseases, including Emery-Dreifuss muscular dystrophy and certain forms of cancer.
Studying the function and regulation of EMD is crucial for understanding its role in these diseases and for developing potential therapeutic strategies.Researchers interested in exploring the function of EMD in cell biology, nuclear envelope structure, and disease pathology will find the EMD Polyclonal Antibody (CAB13925) to be a valuable tool for their studies. Its high reactivity and specificity make it an ideal choice for investigating the molecular mechanisms underlying EMD-mediated processes.
Product Name:
Emerin/EMD Rabbit Polyclonal Antibody
SKU:
CAB13925
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Emerin/Emerin/EMD (NP_000108.1).
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Purification Method:
Affinity purification
Gene ID:
2010
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Emerin/EMD Rabbit pAb (CAB13925) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
