The EMC6 Antibody (PAC030662) is a polyclonal antibody specifically designed for research involving the EMC6 protein, which plays a pivotal role in protein folding and quality control within the endoplasmic reticulum. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a reliable tool for Western blot applications.EMC6 is involved in the maintenance of proper protein folding and trafficking in the ER, ensuring the correct functioning of various cellular processes. By targeting the EMC6 protein, researchers can gain insight into its role in protein quality control and its potential implications in diseases related to ER stress and protein misfolding.
The EMC6 Antibody is a valuable tool for studying the function of EMC6 in different cell types, making it suitable for research in cell biology, protein folding mechanisms, and ER stress-related diseases. Its high specificity and sensitivity make it an essential component in investigations aiming to elucidate the molecular mechanisms underlying ER quality control processes.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO30662 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO30662 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human colon cancer using PACO30662 at dilution of 1:100.
Background:
ER membrane protein complex, integral component of endoplasmic reticulum membrane, integral component of membrane, integral component of omegasome membrane, autophagosome assembly, protein folding in endoplasmic reticulum
Synonyms:
ER membrane protein complex subunit 6 (Transmembrane protein 93), EMC6, TMEM93
UniProt Protein Function:
TMEM93: Belongs to the EMC6 family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17p13.2Cellular Component: integral to endoplasmic reticulum membrane; integral to membraneMolecular Function: protein bindingBiological Process: autophagic vacuole formation
