The ELP2 Polyclonal Antibody (CAB15857) is a valuable tool for researchers studying the ELP2 protein, a subunit of the Elongator complex involved in RNA polymerase II transcription. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ELP2 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and gene regulation.
ELP2 is a crucial component of the Elongator complex, which is known to play a role in transcriptional elongation and tRNA modification. Dysregulation of the Elongator complex has been linked to neurodegenerative diseases and cancer, making the ELP2 protein an important target for research in these areas. Understanding the function of ELP2 and its role in gene expression can provide valuable insights into disease mechanisms and potential therapeutic targets.
Product Name:
ELP2 Rabbit Polyclonal Antibody
SKU:
CAB15857
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human ELP2 (NP_001229808.1).
The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.
Purification Method:
Affinity purification
Gene ID:
55250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELP2 Rabbit pAb (CAB15857) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
