The Elovl4 Polyclonal Antibody (CAB3639) is a valuable tool for researchers studying Elovl4, an enzyme involved in the elongation of very long-chain fatty acids. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the Elovl4 protein, this antibody enables researchers to detect and analyze the enzyme in various cell types, making it an essential tool for studies in lipid metabolism, vision research, and neurological disorders.Elovl4 is known for its role in the synthesis of very long-chain fatty acids, which are essential components of cell membranes and play a critical role in various cellular processes.
Dysregulation of Elovl4 has been linked to disorders such as Stargardt disease and spinocerebellar ataxia. By understanding the function and regulation of Elovl4, researchers can gain insights into the pathophysiology of these diseases and potentially identify therapeutic targets for treatment.Overall, the Elovl4 Polyclonal Antibody (CAB3639) is a reliable reagent that can help advance research in lipid metabolism, vision disorders, and neurodegenerative diseases. Its specificity and sensitivity make it a valuable asset for scientists studying the role of Elovl4 in health and disease.
Product Name:
ELOVL4 Rabbit Polyclonal Antibody
SKU:
CAB3639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELOVL4 (NP_073563.1).
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
Purification Method:
Affinity purification
Gene ID:
6785
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-431 cells, using ELOVL4 Rabbit pAb (CAB3639) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
