Based on the information in the URL, the ELOVL3 Polyclonal Antibody (PACO05453) is a valuable tool for researchers studying ELOVL3, an enzyme involved in the elongation of long-chain fatty acids. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.ELOVL3 is a key player in lipid metabolism and has been implicated in various physiological processes, such as skin barrier function and energy homeostasis. Dysregulation of ELOVL3 has been linked to metabolic disorders and skin diseases, making it a promising target for research in these areas.
The ELOVL3 Polyclonal Antibody enables researchers to detect and analyze the expression of ELOVL3 in different cell types, providing valuable insights into its role in lipid biosynthesis and related pathways.Overall, the ELOVL3 Polyclonal Antibody is a reliable tool for investigating the function of ELOVL3 in health and disease. Its specificity and sensitivity make it an essential reagent for studies focusing on lipid metabolism, skin biology, and metabolic disorders.
Antibody Name:
ELOVL3 Antibody (PACO05453)
Antibody SKU:
PACO05453
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:20000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human ELOVL3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ELOVL3; CIG30; Elongation of very long chain fatty acids protein 3; 3-keto acyl-CoA synthase ELOVL3; Cold-inducible glycoprotein of 30 kDa; ELOVL fatty acid elongase 3; ELOVL FA elongase 3
UniProt Protein Function:
ELOVL3: Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. Belongs to the ELO family.Protein type: Membrane protein, multi-pass; EC 2.3.1.199; Membrane protein, integralChromosomal Location of Human Ortholog: 10q24.32Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membraneMolecular Function: transferase activity; protein bindingBiological Process: circadian rhythm; very-long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; fatty acid elongation, saturated fatty acid; cellular lipid metabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that belongs to the GNS1/SUR4 family. Members of this family play a role in elongation of long chain fatty acids to provide precursors for synthesis of sphingolipids and ceramides. [provided by RefSeq, Jul 2013]
