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ELOVL1 Antibody (PACO00755)

SKU:
PACO00755
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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ELOVL1 Antibody (PACO00755)

The ELOVL1 Polyclonal Antibody (PACO00755) is a valuable tool for researchers studying the ELOVL1 protein, a key enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ELOVL1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it essential for studies in metabolic disorders, lipid metabolism, and related fields.ELOVL1 is a crucial enzyme in the elongation of very long-chain fatty acids, playing a vital role in lipid biosynthesis and homeostasis.

Dysregulation of ELOVL1 has been linked to various metabolic disorders, including obesity, diabetes, and cardiovascular diseases. Research on ELOVL1 is essential for understanding the mechanisms underlying these conditions and developing targeted therapies to address them.Overall, the ELOVL1 Polyclonal Antibody is a valuable tool for researchers looking to investigate the role of ELOVL1 in lipid metabolism and metabolic disorders, ultimately contributing to advancements in the field of metabolic research.

Antibody Name:ELOVL1 Antibody
Antibody SKU:PACO00755
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the Internal region of human ELOVL1.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ELOVL1; SSC1; CGI-88; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1
UniProt Protein Function:ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.
UniProt Protein Details:

Protein type:EC 2.3.1.199; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane

Molecular Function:fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process

UniProt Code:Q9BW60
NCBI GenInfo Identifier:20137931
NCBI Gene ID:64834
NCBI Accession:Q9BW60.1
UniProt Secondary Accession:Q9BW60,Q53HT2, Q5JUY3, Q8WXU3, Q9NVD9, Q9Y396, B4DP24
UniProt Related Accession:Q9BW60
Molecular Weight:29,485 Da
NCBI Full Name:Elongation of very long chain fatty acids protein 1
NCBI Synonym Full Names:ELOVL fatty acid elongase 1
NCBI Official Symbol:ELOVL1  
NCBI Official Synonym Symbols:Ssc1; CGI-88  
NCBI Protein Information:elongation of very long chain fatty acids protein 1
UniProt Protein Name:Elongation of very long chain fatty acids protein 1
UniProt Synonym Protein Names:3-keto acyl-CoA synthase ELOVL1
Protein Family:Elongation of very long chain fatty acids protein
UniProt Gene Name:ELOVL1  
UniProt Entry Name:ELOV1_HUMAN

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