The Elongin A2 Polyclonal Antibody (CAB8492) is a valuable tool for researchers studying Elongin A2, a protein involved in transcriptional regulation and DNA repair processes. This antibody, produced in rabbits, is highly specific and reliable for detecting Elongin A2 in human samples, making it ideal for use in Western blot applications. By targeting the Elongin A2 protein, researchers can gain insights into its functions and interactions within various cellular pathways.Elongin A2 is a component of the Elongin complex, which plays a crucial role in regulating gene expression and maintaining genomic stability.
Dysregulation of Elongin A2 has been linked to various diseases, including cancer and genetic disorders. Studying the role of Elongin A2 using this antibody may provide valuable information for developing targeted therapies and understanding the molecular mechanisms underlying these diseases.Overall, the Elongin A2 Polyclonal Antibody is a key tool for researchers interested in studying the functions and importance of Elongin A2 in cellular processes and disease development. Its high specificity and sensitivity make it a valuable asset for studies in molecular biology, cancer research, and genetic disorders.
Product Name:
TCEB3B Rabbit Polyclonal Antibody
SKU:
CAB8492
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 534-753 of human TCEB3B (NP_057511.2).
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
Purification Method:
Affinity purification
Gene ID:
51224
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TCEB3B antibody (CAB8492) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
