TCEB3 Rabbit Polyclonal Antibody (CAB6994)
- SKU:
- CAB6994
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | TCEB3 Rabbit Polyclonal Antibody |
SKU: | CAB6994 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 679-798 of human TCEB3 (NP_003189.2). |
Sequence: | ANKP KGRQ AKMA FVNS VAKP PRDV RRRQ EKFG TGGA AVPE KIKI KPAP YPMG SSHA SASS ISFN PSPE EPAY DGPS TSSA HLAP VVSS TVSY DPRK PTVK KIAP MMAK TIKA FKNR FSRR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SIII; TCEB3; TCEB3A; SIII p110 |
Positive Sample: | BT-474,HeLa,Raji,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 90kDa |
Observed MW: | 105kDa |
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Purification Method: | Affinity purification |
Gene ID: | 6924 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |