The ELMO3 Polyclonal Antibody (CAB7532) is a valuable tool for researchers studying the protein ELMO3, a key regulator of cell migration and actin cytoskeleton dynamics. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications.ELMO3 plays a crucial role in various cellular processes, including cell motility, invasion, and phagocytosis. By targeting the ELMO3 protein, researchers can investigate its function in different cell types and unravel its involvement in biological pathways related to cancer metastasis, inflammation, and immune response regulation.
With its specificity and sensitivity, the ELMO3 Polyclonal Antibody is an essential tool for researchers interested in understanding the molecular mechanisms underlying cell migration and invasion, potentially leading to novel insights into disease progression and therapeutic targeting strategies.
Product Name:
ELMOD3 Rabbit Polyclonal Antibody
SKU:
CAB7532
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-381 of human ELMOD3 (NP_001128493.1).
This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
84173
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELMOD3 Rabbit pAb (CAB7532) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
