The Elmo2 Polyclonal Antibody (CAB13785) is a valuable tool for researchers studying the Elmo2 protein, which plays a crucial role in cell migration and phagocytosis. This antibody, produced in rabbits, is highly specific to Elmo2 and is suitable for use in various applications such as Western blot and immunofluorescence.Elmo2 is known to interact with Dock180, forming an important complex involved in Rac GTPase activation and cytoskeletal rearrangements that are essential for cell migration and phagocytosis processes. By targeting Elmo2, researchers can gain insights into the mechanisms underlying these cellular functions and potentially uncover new therapeutic targets for diseases involving abnormal cell migration or phagocytosis.
With its high sensitivity and specificity, the Elmo2 Polyclonal Antibody (CAB13785) is a reliable tool for investigating the role of Elmo2 in cellular processes and disease pathogenesis. Its utility in various research applications makes it a valuable asset for studies in cell biology, immunology, and cancer research.
Product Name:
ELMO2 Rabbit Polyclonal Antibody
SKU:
CAB13785
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-120 of human ELMO2 (NP_877496.1).
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
63916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELMO2 Rabbit pAb (CAB13785) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
