The ELL Polyclonal Antibody (CAB16448) is a valuable tool for researchers studying the ELL protein, a key player in transcriptional elongation regulation. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ELL protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and gene expression research.ELL is a transcription elongation factor that plays a crucial role in the regulation of RNA polymerase II-mediated transcription.
Dysregulation of ELL has been implicated in various diseases, including cancer and developmental disorders. Therefore, exploring the function and mechanisms of ELL is essential for understanding these conditions and developing targeted therapies.By utilizing the ELL Polyclonal Antibody, researchers can gain valuable insights into the role of ELL in transcriptional regulation, providing a deeper understanding of gene expression dynamics and offering potential avenues for therapeutic intervention.
Product Name:
ELL Rabbit Polyclonal Antibody
SKU:
CAB16448
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human ELL (NP_006523.1).
Enables phosphatase binding activity. Involved in positive regulation of transcription, DNA-templated and snRNA transcription. Located in cytosol; nuclear body; and transcriptionally active chromatin. Part of transcription elongation factor complex.
Purification Method:
Affinity purification
Gene ID:
8178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELL Rabbit pAb (CAB16448) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
