The Elk1 Polyclonal Antibody (CAB0789) is a powerful tool for researchers studying Elk1, a transcription factor involved in the regulation of gene expression. This antibody, generated in rabbits, has high specificity for Elk1 and has been validated for use in Western blotting applications. By targeting Elk1, this antibody allows for the detection and analysis of Elk1 protein levels in various cell types, providing valuable insights for studies in molecular biology and cancer research.Elk1 plays a pivotal role in controlling gene expression in response to various cellular signals, making it a key player in processes such as cell proliferation, differentiation, and survival.
Dysregulation of Elk1 has been implicated in various diseases, including cancer and neurodegenerative disorders. By studying Elk1 with the help of this antibody, researchers can gain a better understanding of its function and potential therapeutic targets for related conditions.Overall, the Elk1 Polyclonal Antibody (CAB0789) offers researchers a reliable tool for investigating Elk1 biology and its implications in various disease states. Its high specificity and sensitivity make it a valuable asset for studies aiming to unravel the complex mechanisms of gene regulation and cellular signaling pathways.
Product Name:
ELK1 Rabbit Polyclonal Antibody
SKU:
CAB0789
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-297 of human ELK1 (NP_005220.2).
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14.
Purification Method:
Affinity purification
Gene ID:
2002
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ELK1 antibody (CAB0789) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
