ELF5 Transcription Factor Activity Assay
- SKU:
- TFAB00095
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- ELF5
- Reactivity:
- Human
- Mouse
Description
ELF5 Transcription Factor Activity Assay
The ELF5 Transcription Factor Activity Assay is a vital tool for researchers studying gene regulation and transcriptional activity. This assay kit is designed to accurately measure the activity of the ELF5 transcription factor in various biological samples, including cell lysates and tissue extracts.ELF5 is a key transcription factor that plays a critical role in regulating gene expression and cell differentiation. Dysregulation of ELF5 activity has been linked to various diseases, including cancer, developmental disorders, and immune dysfunction.
By accurately measuring ELF5 activity, researchers can gain valuable insights into the molecular mechanisms underlying these conditions.The ELF5 Transcription Factor Activity Assay offers high sensitivity and specificity, allowing for precise quantification of ELF5 activity in a wide range of experimental conditions. With reliable and reproducible results, this assay kit is an essential tool for researchers looking to advance our understanding of gene regulation and develop potential therapeutic strategies.
| Product Name: | ELF5 Transcription Factor Activity Assay |
| Product Code: | TFAB00095 |
| Target: | ELF5 |
| Synonyms: | E74-like factor 5, Epithelium-restricted ESE-1-related Ets factor, Epithelium-specific Ets transcription factor 2, ESE-2 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie ELF5 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | ELF5: Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. Belongs to the ETS family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 11p13-p12 Cellular Component: nucleus Biological Process: cell differentiation; cell proliferation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q9UKW6 |
| NCBI GenInfo Identifier: | 68565549 |
| NCBI Gene ID: | 2001 |
| NCBI Accession: | Q9UKW6.2 |
| UniProt Secondary Accession: | Q9UKW6,O95175, Q8N2K9, Q96QY3, Q9UKW5, A6XAE6, A8K452 |
| UniProt Related Accession: | Q9UKW6 |
| Molecular Weight: | 18,866 Da |
| NCBI Full Name: | ETS-related transcription factor Elf-5 |
| NCBI Synonym Full Names: | E74 like ETS transcription factor 5 |
| NCBI Official Symbol: | ELF5Â Â |
| NCBI Official Synonym Symbols: | ESE2Â Â |
| NCBI Protein Information: | ETS-related transcription factor Elf-5 |
| UniProt Protein Name: | ETS-related transcription factor Elf-5 |
| UniProt Synonym Protein Names: | E74-like factor 5; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2 |
| Protein Family: | ETS-related transcription factor |
| UniProt Gene Name: | ELF5Â Â |
| UniProt Entry Name: | ELF5_HUMAN |
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