The ELF3 Polyclonal Antibody (CAB13489) is a valuable tool for studying the ELF3 protein, a transcription factor involved in various cellular processes including cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, has high specificity for ELF3 in human samples and is validated for use in Western blot applications.ELF3, also known as ESE-1, is a key regulator of gene expression and plays a crucial role in controlling cell growth and development. Dysregulation of ELF3 has been implicated in a variety of diseases, including cancer, making it a promising target for therapeutic intervention.
By using the ELF3 Polyclonal Antibody, researchers can accurately detect and analyze ELF3 protein levels in different cell types, advancing our understanding of its functions in health and disease.Whether studying the role of ELF3 in cancer progression, cell differentiation, or other biological processes, the ELF3 Polyclonal Antibody is a reliable reagent for high-quality research. Its specificity, sensitivity, and compatibility with various experimental techniques make it an essential tool for investigations in molecular biology, oncology, and beyond.
Product Name:
ESE1/ELF3 Rabbit Polyclonal Antibody
SKU:
CAB13489
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ESE1/ESE1/ELF3 (NP_004424.3).
WB,1:100 - 1:500 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
ERT; ESX; EPR-1; ESE-1; ESE1/ELF3
Positive Sample:
A-431,SK-BR-3
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
41kDa
Observed MW:
47kDa
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in inflammatory response; negative regulation of transcription, DNA-templated; and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus; cytosol; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
1999
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ESE1/ELF3 Rabbit pAb (CAB13489) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
