The ELAVL4 Rabbit Polyclonal Antibody is a valuable tool for researchers studying ELAVL4, a protein involved in post-transcriptional regulation of gene expression. This antibody is produced in rabbits and is highly specific to ELAVL4 in human samples. It has been validated for use in techniques such as Western blotting, immunofluorescence, and immunohistochemistry.ELAVL4, also known as HuD, is a neuronal RNA-binding protein that plays a crucial role in the development and function of the nervous system.
Dysregulation of ELAVL4 has been implicated in neurological disorders such as Alzheimer's disease and epilepsy, making it a promising target for therapeutic interventions. By using this antibody, researchers can study the expression and localization of ELAVL4 in various cell types and tissues, providing insights into its functions and potential implications for human health.
Product Name:
ELAVL4 Rabbit Polyclonal Antibody
SKU:
CAB10655
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELAVL4 (NP_068771.2).
Enables mRNA 3'-UTR AU-rich region binding activity; poly(A) binding activity; and pre-mRNA intronic pyrimidine-rich binding activity. Involved in 3'-UTR-mediated mRNA stabilization; RNA processing; and positive regulation of 3'-UTR-mediated mRNA stabilization. Predicted to be located in axon; cytoplasm; and dendrite. Predicted to be part of polysomal ribosome. Predicted to be active in glutamatergic synapse.
Purification Method:
Affinity purification
Gene ID:
1996
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELAVL4 Rabbit pAb (CAB10655) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
