ELAVL2 Rabbit Polyclonal Antibody (CAB5918)
- SKU:
- CAB5918
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ELAVL2 Rabbit Polyclonal Antibody |
SKU: | CAB5918 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELAVL2 (NP_004423.2). |
Sequence: | METQ LSNG PTCN NTAN GPTT INNN CSSP VDSG NTED SKTN LIVN YLPQ NMTQ EELK SLFG SIGE IESC KLVR DKIT GQSL GYGF VNYI DPKD AEKA INTL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HUB; HELN1; HEL-N1; ELAVL2 |
Positive Sample: | SH-SY5Y,Mouse spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm |
Calculated MW: | 40kDa |
Observed MW: | 44kDa |
In humans, the ELAV like RNA binding protein gene family has four members (ELAVL1-4). ELAVL RNA binding proteins recognize AU-rich elements in the 3' UTRs of gene transcripts and thereby regulate gene expression post-transcriptionally. The protein encoded by this gene binds to several 3' UTRs, including its own and also that of FOS, ID, and POU5F1. This gene encodes ELAVL2 and, like ELAVL3 and ELAVL4, is expressed specifically in neurons and primarily localizes to the cytoplasm. This protein also forms a cytosolic complex with the normally nuclear-localized ELAVL1 protein. Alternative splicing of this gene results in multiple transcript variants encoding distinct protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1993 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |