The Elav Like Protein 3 Polyclonal Antibody (CAB6091) is a valuable tool for researchers studying Elav Like Protein 3, a member of the RNA-binding protein family that plays a crucial role in post-transcriptional regulation of gene expression. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blot applications.Elav Like Protein 3 is known for its ability to bind to mRNA and regulate its stability and translation, influencing various cellular processes such as cell differentiation, proliferation, and apoptosis. Its dysregulation has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and developmental abnormalities, making it an attractive target for further investigation.
By enabling the detection and analysis of Elav Like Protein 3 in different cell types, the CAB6091 antibody provides researchers with a powerful tool for exploring the molecular mechanisms underlying Elav Like Protein 3 function and its potential role in disease pathogenesis. This antibody is an essential resource for studies in molecular biology, cell biology, and biomedicine, facilitating advancements in our understanding of RNA metabolism and its implications for human health.
Product Name:
ELAVL3 Rabbit Polyclonal Antibody
SKU:
CAB6091
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 161-260 of human ELAVL3 (NP_001411.2).
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1995
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ELAVL3 Rabbit pAb (CAB6091) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.8s.
