[KO Validated] HuR/ELAVL1 Rabbit Polyclonal Antibody (CAB1608)
- SKU:
- CAB1608
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] HuR/ELAVL1 Rabbit Polyclonal Antibody |
SKU: | CAB1608 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human HuR/ELAVL1 (NP_001410.2). |
Sequence: | MSNG YEDH MAED CRGD IGRT NLIV NYLP QNMT QDEL RSLF SSIG EVES AKLI RDKV AGHS LGYG FVNY VTAK DAER AINT LNGL RLQS KTIK VSYA RPSS EVIK DANL YISG LPRT MTQK DVED MFSR FGRI INSR VLVD QTTG LSRG VAFI RFDK RSEA EEAI TSFN GHKP PGSS EPIT VKFA ANPN QNKN VALL SQLY HSPA RRFG GPVH HQAQ RFRF SPMG VDHM SGLS GVNV PGNA SSGW CIFI YNLG QDAD EGIL WQMF GPFG AVTN VKVI RDFN TNKC KGFG FVTM TNYE EAAM AIAS LNGY RLGD KILQ VSFK TNKS HK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HUR; Hua; MelG; ELAV1; L1 |
Positive Sample: | U-251MG,HeLa,Jurkat,K-562,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 37kDa |
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Purification Method: | Affinity purification |
Gene ID: | 1994 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |