EIF6 Rabbit Polyclonal Antibody (CAB1818)
- SKU:
- CAB1818
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | EIF6 Rabbit Polyclonal Antibody |
SKU: | CAB1818 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human EIF6 (NP_852133.1). |
Sequence: | MAVR ASFE NNCE IGCF AKLT NTYC LVAI GGSE NFYS VFEG ELSD TIPV VHAS IAGC RIIG RMCV GNRH GLLV PNNT TDQE LQHI RNSL PDTV QIRR VEER LSAL GNVT TCND YVAL VHPD LDRE TEEI LADV LKVE VFRQ TVAD QVLV GSYC VFSN QGGL VHPK TSIE DQDE LSSL LQVP LVAG TVNR GSEV IAAG MVVN DWCA FCGL DTTS TELS VVES VFKL NEAQ PSTI ATSM RDSL IDSL T |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CAB; EIF3A; eIF-6; p27BBP; ITGB4BP; b(2)gcn; p27(BBP); EIF6 |
Positive Sample: | HepG2,293F,C2C12,Mouse liver,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3692 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |