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EIF5A Monoclonal Antibody [PAT2E9AT] (CPAB0430)

SKU:
CPAB0430
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT2E9AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

EIF5A Monoclonal Antibody [PAT2E9AT] (CPAB0430)

The EIF5A Polyclonal Antibody (CPAB0430) is a valuable tool for research involving EIF5A, a protein involved in the regulation of protein synthesis and cell proliferation. The antibody is produced in rabbits and has a high specificity for human samples, making it reliable for use in Western blot applications. With the ability to bind to the EIF5A protein, this antibody enables the detection and analysis of EIF5A in various cell types, making it ideal for studies in molecular biology and cancer research.EIF5A is a key player in the translation elongation process and is known to be dysregulated in various cancers, making it a potential target for cancer therapy.

By understanding the function of EIF5A, researchers can gain insights into its role in cell growth and proliferation, as well as its potential as a therapeutic target for cancer treatment. The EIF5A Polyclonal Antibody is a valuable tool for investigating the mechanisms underlying EIF5A's involvement in cancer and other diseases, paving the way for the development of novel treatment strategies.

Product Name:EIF5A Antibody
Product Sku:CPAB0430
Size:5μg
Host Species:Mouse
Immunogen:Anti-human EIF5A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EIF5A amino acids 1-154 purified from Ecoli.
Clone:PAT2E9AT.
Reactivity:Other bodies
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:EIF5A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:EIF5A is the single protein identified to contain remarkable amino acid formed by the action of deoxyhypusine synthase and deoxyhypusine hydroxylase using spermidine as the substrate. EIF5A takes part in the first step of peptide bond formation in translation, nevertheless further experiments implicates it as a universally conserved translation elongation factor. Modulation of EIF5A is connected to proliferation and cancer. Expression of EIF-5A is upregulated in the PBMCs of HIV-1 patients. EIF5A coordinates significant cellular processes like cell viability and senescence during its effects on the stability of certain mRNAs. Heat stress-induced loss of EIF-5A in a human pancreatic cancer cell line. EIF5A stability takes part in determining the fate of the particular cell type after severe heat stress.
Synonyms:EIF-5A, EIF5A1, eIF5AI, MGC99547, MGC104255, EIF5A, Eukaryotic translation initiation factor 5A-1, eIF-5A-1, eIF-5A1, Eukaryotic initiation factor 5A isoform 1, eIF-4D, Rev-binding factor.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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