The EIF4H Polyclonal Antibody (CAB9953) is a valuable tool for researchers studying EIF4H, a key factor in protein synthesis and regulation. Raised in rabbits, this antibody is highly specific for human samples and is validated for use in Western blot applications. By binding to the EIF4H protein, researchers can easily detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and cancer research.EIF4H is a crucial component of the eukaryotic translation initiation factor complex, playing a vital role in the initiation of protein synthesis.
Dysregulation of EIF4H has been implicated in various diseases, including cancer, making it a promising target for therapeutic intervention. Understanding the function and regulation of EIF4H can provide valuable insights into the molecular mechanisms underlying these diseases, ultimately paving the way for the development of novel therapies.
Product Name:
EIF4H Rabbit Polyclonal Antibody
SKU:
CAB9953
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-228 of human EIF4H (NP_114381.1).
This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
Purification Method:
Affinity purification
Gene ID:
7458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EIF4H antibody (CAB9953) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
