EIF4G3 Rabbit Polyclonal Antibody (CAB14621)
- SKU:
- CAB14621
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | EIF4G3 Rabbit Polyclonal Antibody |
SKU: | CAB14621 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human EIF4G3 (NP_003751.2). |
Sequence: | HKEA KIEE QEEQ RKVQ QLMT KEKR RPGV QRVD EGGW NTVQ GAKN SRVL DPSK FLKI TKPT IDEK IQLV PKAQ LGSW GKGS SGGA KASE TDAL RSSA SSLN RFSA LQPP APSG STPS TPVE FDSR RTLT SRGS MGRE KNDK PLPS ATAR PNTF MRGG SSKD LLDN QSQE EQRR EMLE TVKQ LTGG VDVE RNST EAER NKTR E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | eIF4G 3; eIF4GII; eIF-4G 3; EIF4G3 |
Positive Sample: | LO2,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, eukaryotic translation initiation factor 4F complex |
Calculated MW: | 177kDa |
Observed MW: | 250kDa |
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
Purification Method: | Affinity purification |
Gene ID: | 8672 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |