The EIF4ENIF1 Polyclonal Antibody (CAB15175) is a crucial tool for researchers studying EIF4ENIF1, a protein involved in the regulation of mRNA translation in the cytoplasm. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding to EIF4ENIF1, the antibody enables precise detection and analysis in a variety of cell types, making it suitable for investigations in the fields of molecular biology and cancer research.
EIF4ENIF1, also known as EAP1, is a key component in the control of mRNA translation initiation and termination. Its role in fine-tuning gene expression makes it a promising target for research on gene regulation, protein synthesis, and RNA biology. Understanding the function of EIF4ENIF1 is essential for unraveling the complexities of gene expression and potentially discovering novel therapeutic strategies for diseases characterized by dysregulated mRNA translation.
Product Name:
EIF4ENIF1 Rabbit Polyclonal Antibody
SKU:
CAB15175
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EIF4ENIF1 (NP_001157973.1).
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
56478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF4ENIF1 Rabbit pAb (CAB15175) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
