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eIF4EBP1 Rabbit Polyclonal Antibody (CAB16667)

SKU:
CAB16667
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 2 Anti-EIF4EBP1 Antibody CAB16667
  • Signal Transduction Antibodies 2 Anti-EIF4EBP1 Antibody CAB16667
  • Signal Transduction Antibodies 2 Anti-EIF4EBP1 Antibody CAB16667
  • Signal Transduction Antibodies 2 Anti-EIF4EBP1 Antibody CAB16667
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:eIF4EBP1 Rabbit Polyclonal Antibody
SKU:CAB16667
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human eIF4EBP1 (NP_004086.1).
Sequence:MSGG SSCS QTPS RAIP ATRR VVLG DGVQ LPPG DYST TPGG TLFS TTPG GTRI IYDR KFLM ECRN SPVT KTPP RDLP TIPG VTSP SSDE PPME ASQS HLRN SPED KRAG GEES QFEM DI
Tested Applications:IHC-P ELISA
Recommended Dilution:IHC-P,1:50 - 1:200
Synonyms:BP-1; 4EBP1; 4E-BP1; PHAS-I; eIF4EBP1
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol
Calculated MW:13kDa

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Purification Method:Affinity purification
Gene ID:1978
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded human colon carcinoma using eIF4EBP1 Rabbit pAb (CAB16667) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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