The eIF4E3 Polyclonal Antibody (CAB13879) is a vital tool for researchers studying eukaryotic translation initiation factor 4E (eIF4E3), a key protein involved in regulating protein synthesis. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications.eIF4E3 plays a crucial role in translational control and mRNA binding, making it essential for understanding gene expression regulation in various cellular processes. By targeting the eIF4E3 protein, this antibody enables precise detection and analysis in different cell types, facilitating research in molecular biology, cell biology, and developmental biology.
The involvement of eIF4E3 in pathways related to growth, differentiation, and proliferation highlights its significance in normal cellular function and disease states. Research on eIF4E3 can provide insights into cancer biology, neurological disorders, and other conditions where dysregulation of protein synthesis is implicated.By using the eIF4E3 Polyclonal Antibody (CAB13879), researchers can enhance their studies on translational control mechanisms and further our understanding of the molecular processes underlying various diseases, paving the way for potential therapeutic interventions targeting eIF4E3-related pathways.
Product Name:
EIF4E3 Rabbit Polyclonal Antibody
SKU:
CAB13879
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1).
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).
Purification Method:
Affinity purification
Gene ID:
317649
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF4E3 Rabbit pAb (CAB13879) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
