eIF4E Rabbit Monoclonal Antibody (CAB19044)
- SKU:
- CAB19044
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | eIF4E Rabbit Monoclonal Antibody |
SKU: | CAB19044 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 118-217 of human eIF4E (P06730). |
Sequence: | NKQQ RRSD LDRF WLET LLCL IGES FDDY SDDV CGAV VNVR AKGD KIAI WTTE CENR EAVT HIGR VYKE RLGL PPKI VIGY QSHA DTAT KSGS TTKN RFVV |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; eIF4E |
Positive Sample: | Mouse testis,Mouse liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1977 |
Clone Number: | ARC0447 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |