eIF4E Rabbit Polyclonal Antibody (CAB2162)
- SKU:
- CAB2162
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | eIF4E Rabbit Polyclonal Antibody |
SKU: | CAB2162 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF4E (NP_001959.1). |
Sequence: | MATV EPET TPTP NPPT TEEE KTES NQEV ANPE HYIK HPLQ NRWA LWFF KNDK SKTW QANL RLIS KFDT VEDF WALY NHIQ LSSN LMPG CDYS LFKD GIEP |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; 4E |
Positive Sample: | 293T,HeLa,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa/28kDa |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1977 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |