The EIF4B Polyclonal Antibody (CAB13300) is a valuable tool for researchers studying EIF4B, a protein involved in the translation initiation process. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot applications. By targeting the EIF4B protein, this antibody allows for the detection and analysis of EIF4B expression in various cell types, a crucial aspect for studies in molecular biology and cancer research.EIF4B, also known as eukaryotic translation initiation factor 4B, plays a pivotal role in regulating protein synthesis and cell growth.
Aberrant EIF4B expression has been linked to cancer progression and other diseases, highlighting its significance as a therapeutic target. Investigating the functions of EIF4B can provide valuable insights into the mechanisms underlying these conditions, paving the way for the development of novel treatment strategies targeting EIF4B and its associated pathways.
Product Name:
EIF4B Rabbit Polyclonal Antibody
SKU:
CAB13300
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 352-611 of human EIF4B (NP_001408.2).
Enables RNA binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in cytosol. Biomarker of autism spectrum disorder and major depressive disorder.
Purification Method:
Affinity purification
Gene ID:
1975
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat skeletal muscle, using EIF4B antibody (CAB13300) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
