The eIF4A3 Polyclonal Antibody (CAB4338) is a valuable tool for researchers studying eIF4A3, a key component of the eukaryotic translation initiation complex. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications. By targeting the eIF4A3 protein, this antibody enables the accurate detection and analysis of eIF4A3 levels in various cell types, offering insights into its role in gene expression and protein synthesis.eIF4A3 is a crucial RNA helicase that plays a vital role in RNA metabolism and translation initiation. Dysregulation of eIF4A3 has been implicated in various diseases, including cancer and neurological disorders, making it a promising target for therapeutic intervention.
Research focusing on eIF4A3 can provide valuable insights into the molecular mechanisms underlying these conditions and facilitate the development of novel treatment strategies.By utilizing the eIF4A3 Polyclonal Antibody (CAB4338), researchers can advance their understanding of eIF4A3 function and its implications in disease pathology. Whether investigating gene expression regulation, protein synthesis, or disease mechanisms, this antibody serves as a reliable tool for molecular and cellular studies in the fields of biology, biomedicine, and beyond.
Product Name:
eIF4A3 Rabbit Polyclonal Antibody
SKU:
CAB4338
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human eIF4A3 (NP_055555.1).
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.
Purification Method:
Affinity purification
Gene ID:
9775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using eIF4A3 Rabbit pAb (CAB4338) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
