The EIF4A1 Polyclonal Antibody (CAB5294) is a versatile tool for researchers studying EIF4A1, a key protein involved in translation initiation and regulation. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the EIF4A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.EIF4A1 is a critical component of the eukaryotic translation initiation complex, playing a pivotal role in mRNA unwinding and ribosome scanning during protein synthesis.
Dysregulation of EIF4A1 has been implicated in a variety of diseases, including cancer, genetic disorders, and neurological conditions. By understanding the function and regulation of EIF4A1, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
eIF4A1 Rabbit Polyclonal Antibody
SKU:
CAB5294
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF4A1 (NP_001407.1).
Enables double-stranded RNA binding activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
1973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using eIF4A1 Rabbit pAb (CAB5294) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
