The EIF3M Polyclonal Antibody (CAB4426) is a valuable tool for researchers studying EIF3M, a key component of the eukaryotic translation initiation factor 3 (eIF-3) complex. This antibody, produced in rabbits, is highly specific to human EIF3M and has been validated for use in Western blot applications.EIF3M is essential for protein synthesis and plays a crucial role in the regulation of translation initiation. Dysregulation of EIF3M has been linked to various diseases, including cancer, making it a promising target for therapeutic interventions. By detecting and analyzing EIF3M expression in different cell types, this antibody is ideal for studies focusing on protein synthesis, gene expression, and molecular mechanisms involved in disease pathogenesis.
Researchers in the fields of molecular biology, cancer biology, and translational research will benefit from the versatility and reliability of the EIF3M Polyclonal Antibody (CAB4426) in their investigations. Invest in this antibody to advance your understanding of EIF3M function and its potential implications in disease development and treatment strategies.
Product Name:
EIF3M Rabbit Polyclonal Antibody
SKU:
CAB4426
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human EIF3M (NP_006351.2).
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.
Purification Method:
Affinity purification
Gene ID:
10480
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF3M Rabbit pAb (CAB4426) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
