The EIF3J Polyclonal Antibody (CAB8637) is a valuable tool for researchers studying EIF3J, a subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting EIF3J, this antibody allows for the detection and analysis of the protein in various cell types, making it ideal for studies in molecular biology and cancer research.EIF3J is a crucial component of the eIF3 complex, which plays a key role in protein synthesis by mediating the recruitment of ribosomes to mRNA.
Dysregulation of EIF3J has been implicated in various diseases, including cancer, making it a potential therapeutic target. By using the EIF3J Polyclonal Antibody, researchers can further investigate the role of EIF3J in cellular processes, advancing our understanding of its functions and potential implications in disease development and progression.
Product Name:
EIF3J Rabbit Polyclonal Antibody
SKU:
CAB8637
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human EIF3J (NP_003749.2).
This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
8669
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF3J Rabbit pAb (CAB8637) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
