The EIF3G Polyclonal Antibody (CAB4240) is a valuable tool for researchers studying EIF3G, a key component of the eukaryotic translation initiation factor 3 (eIF3) complex. This antibody, generated in rabbits, is specifically designed to recognize EIF3G in human samples and is validated for use in Western blot applications. By targeting EIF3G, researchers can investigate its role in protein synthesis and cellular processes, providing insights into gene regulation, cell growth, and development.
EIF3G is essential for the initiation of translation, facilitating the assembly of the ribosome-mRNA complex necessary for protein synthesis. Dysregulation of EIF3G has been linked to various diseases, including cancer, genetic disorders, and neurological conditions. By studying EIF3G with this antibody, researchers can uncover its molecular functions and contribution to disease pathology, paving the way for potential therapeutic interventions targeting EIF3G-related pathways.
Product Name:
EIF3G Rabbit Polyclonal Antibody
SKU:
CAB4240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human EIF3G (NP_003746.2).
This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy.
Purification Method:
Affinity purification
Gene ID:
8666
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EIF3G antibody (CAB4240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
