The EIF3C Polyclonal Antibody (CAB7022) is specifically designed for research involving EIF3C, a subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. EIF3C plays a crucial role in protein synthesis by aiding in the initiation of mRNA translation. Dysregulation of EIF3C has been implicated in various diseases, including cancer, making it a valuable target for research in oncology and other fields.
With the ability to bind to EIF3C protein, this antibody enables the detection and analysis of EIF3C in different cell types, making it a versatile tool for studies in molecular biology and cancer research. Understanding the function and regulation of EIF3C is essential for gaining insights into protein synthesis processes and developing targeted therapies for diseases associated with its dysregulation.
Product Name:
EIF3C Rabbit Polyclonal Antibody
SKU:
CAB7022
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 694-913 of human EIF3C (NP_003743.1).
Enables ribosome binding activity. Contributes to translation initiation factor activity. Involved in positive regulation of mRNA binding activity; positive regulation of translation; and translational initiation. Part of eukaryotic translation initiation factor 3 complex.
Purification Method:
Affinity purification
Gene ID:
8663
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF3C Rabbit pAb (CAB7022) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
