The EIF3A Polyclonal Antibody (CAB0573) is a valuable tool for researchers studying EIF3A, a vital component of the eukaryotic translation initiation factor 3 (eIF3) complex. This antibody, produced in rabbits, specifically targets EIF3A in human samples and is validated for use in applications such as Western blotting.EIF3A is essential for protein synthesis initiation and regulation, playing a crucial role in cell growth, proliferation, and differentiation. Dysregulation of EIF3A has been linked to various diseases, including cancer and neurological disorders.
By targeting EIF3A, researchers can gain insight into the mechanisms underlying these conditions and develop potential therapeutic strategies.With its high reactivity and specificity, the EIF3A Polyclonal Antibody allows for reliable detection and analysis of EIF3A in different cell types and tissues. Its versatility makes it a valuable asset for studies in molecular biology, oncology, and neurology, advancing our understanding of EIF3A function and its implications in health and disease.
Product Name:
EIF3A Rabbit Polyclonal Antibody
SKU:
CAB0573
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_003741.1).
Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of cytoplasmic translation initiation complex; and viral translational termination-reinitiation. Located in cytosol; nucleolus; and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex.
Purification Method:
Affinity purification
Gene ID:
8661
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of RAW 264.7, using EIF3A Rabbit pAb (CAB0573) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
