The EIF2S2 Polyclonal Antibody (CAB17040) is a valuable tool for researchers studying eukaryotic translation initiation factor 2 subunit 2 (EIF2S2), a key regulator of protein synthesis in cells. This rabbit polyclonal antibody is highly specific for EIF2S2 and is suitable for use in Western blot applications. By binding to EIF2S2, researchers can detect and analyze protein levels in various cell types, enabling insights into the role of EIF2S2 in cellular processes.EIF2S2 is essential for the initiation of protein translation in response to cellular stress, making it a crucial player in the regulation of protein synthesis.
Dysregulation of EIF2S2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. By studying EIF2S2 using this antibody, researchers can uncover its role in disease pathogenesis and potentially identify targets for therapeutic interventions aimed at restoring normal protein synthesis dynamics.Overall, the EIF2S2 Polyclonal Antibody (CAB17040) offers researchers a reliable tool to explore the functions of EIF2S2 in cellular processes and disease contexts, laying the groundwork for future advancements in biomedicine.
Product Name:
EIF2S2 Rabbit Polyclonal Antibody
SKU:
CAB17040
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human EIF2S2 (NP_003899.2).
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8894
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF2S2 Rabbit pAb (CAB17040) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
