The EIF2S2 Polyclonal Antibody (CAB14498) is a valuable tool for researchers studying EIF2S2, a key protein involved in the process of protein synthesis in cells. This antibody, derived from rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the EIF2S2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.
EIF2S2, also known as eukaryotic translation initiation factor 2 subunit 2, plays a crucial role in the regulation of protein synthesis and cellular response to stress. Dysregulation of EIF2S2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. By understanding the function and expression of EIF2S2, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
Product Name:
EIF2S2 Rabbit Polyclonal Antibody
SKU:
CAB14498
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human EIF2S2 (NP_003899.2).
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8894
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF2S2 Rabbit pAb (CAB14498) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
