The EIF2C2 Polyclonal Antibody (CAB6023) is specifically designed for research involving EIF2C2, a key player in RNA interference and microRNA regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the EIF2C2 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in molecular biology and cancer research.EIF2C2, also known as Ago2, is a critical component of the RNA-induced silencing complex (RISC) and is essential for gene regulation at the post-transcriptional level.
Its involvement in RNA interference pathways underscores its importance in cellular processes such as mRNA degradation and translational repression. Research on EIF2C2 is vital for understanding the regulatory mechanisms of gene expression and exploring its potential implications in diseases like cancer and viral infections. By elucidating the functions of EIF2C2, researchers can uncover new therapeutic targets and strategies for treating various disorders at the molecular level.
Product Name:
Argonaute-2 Rabbit Polyclonal Antibody
SKU:
CAB6023
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Argonaute-2 (NP_036286.2).
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27161
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Argonaute-2 Rabbit pAb (CAB6023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
