The EIF2B4 Polyclonal Antibody (CAB18203) is a valuable tool for researchers studying EIF2B4, a key regulatory protein involved in protein synthesis and cellular stress responses. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications. By binding to the EIF2B4 protein, this antibody enables the detection and analysis of EIF2B4 in various cell types, facilitating investigations in molecular biology and cell signaling pathways.EIF2B4, a subunit of the eukaryotic translation initiation factor 2B (eIF2B) complex, plays a crucial role in the control of protein synthesis in response to cellular stress signals. Dysregulation of EIF2B4 has been associated with a variety of human diseases, including neurodegenerative disorders and certain types of cancer.
Therefore, elucidating the function and regulation of EIF2B4 is essential for understanding the molecular basis of these diseases and exploring potential therapeutic strategies.With its high specificity and reliability, the EIF2B4 Polyclonal Antibody (CAB18203) offers researchers a powerful tool for investigating the role of EIF2B4 in cellular processes and disease pathogenesis. Its applications in Western blotting provide valuable insights into the expression levels and post-translational modifications of EIF2B4, advancing our understanding of its functions in health and disease.
Product Name:
EIF2B4 Rabbit Polyclonal Antibody
SKU:
CAB18203
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human EIF2B4 (Q9UI10).
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8890
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EIF2B4 Rabbit pAb (CAB18203) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
