EIF2B3 Rabbit Polyclonal Antibody (CAB10262)
- SKU:
- CAB10262
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | EIF2B3 Rabbit Polyclonal Antibody |
SKU: | CAB10262 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EIF2B3 (NP_065098.1). |
Sequence: | MEFQ AVVM AVGG GSRM TDLT SSIP KPLL PVGN KPLI WYPL NLLE RVGF EEVI VVTT RDVQ KALC AEFK MKMK PDIV CIPD DADM GTAD SLRY IYPK LKTD VLVL SCDL ITDV ALHE VVDL FRAY DASL AMLM RKGQ DSIE PVPG QKGK KKAV EQRD FIGV DSTG KRLL FMAN EADL DEEL VIKG SILQ KHPR IRFH TGLV DAHL YCLK KYIV DFLM ENGS ITSI RSEL IPYL VRKQ FSSA SSQQ GQEE KEED LKKK ELKS LDIY SFIK EA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | EIF-2B; EIF2Bgamma; EIF2B3 |
Positive Sample: | HepG2,K-562,HT-29,Mouse heart,Mouse lung,Mouse brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8891 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |