The EIF2B1 Polyclonal Antibody (CAB7892) is a valuable tool for researchers studying EIF2B1, a subunit of eukaryotic translation initiation factor 2B (eIF-2B) involved in protein synthesis regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.EIF2B1 plays a crucial role in the regulation of translation initiation, a process essential for protein synthesis in cells. Dysregulation of EIF2B1 has been linked to a variety of diseases, including neurological disorders and cancer.
By targeting EIF2B1 with this polyclonal antibody, researchers can gain insights into its function and potential implications in disease pathology.With its high reactivity and specificity, the EIF2B1 Polyclonal Antibody is an ideal tool for studying EIF2B1 expression levels and localization in various cell types. It is a valuable asset for researchers in the fields of molecular biology, cell biology, and neurobiology seeking to unravel the complexities of protein synthesis regulation and its role in disease development.
Product Name:
EIF2B1 Rabbit Polyclonal Antibody
SKU:
CAB7892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human EIF2B1 (NP_001405.1).
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Purification Method:
Affinity purification
Gene ID:
1967
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EIF2B1 antibody (CAB7892) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
