GCN2 Rabbit Polyclonal Antibody (CAB12618)
- SKU:
- CAB12618
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | GCN2 Rabbit Polyclonal Antibody |
SKU: | CAB12618 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCN2 (NP_001013725.2). |
Sequence: | MAGG RGAP GRGR DEPP ESYP QRQD HELQ ALEA IYGA DFQD LRPD ACGP VKEP PEIN LVLY PQGL TGEE VYVK VDLR VKCP PTYP DVVP EIEL KNAK GLSN ESVN LLKS RLEE LAKK HCGE VMIF ELAY HVQS FLSE HNKP PPKS FHEE MLER RAQE EQQR LLEA KRKE EQEQ REIL HEIQ RRKE EIKE EKKR KEMA KQER LEIA SLSN QDHT SKKD PGGH RTAA ILHG GSPD FVGN GKHR ANSS GRSR RERQ YSVC NSED SPGS CEIL YFNM GSPD QLMV HKGK CIGS DEQL GKLV YNAL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | GCN2; PVOD2 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, cytosolic ribosome |
Calculated MW: | 187kDa |
Observed MW: | 187kDa |
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Purification Method: | Affinity purification |
Gene ID: | 440275 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |