The EIF2AK1 Polyclonal Antibody (CAB14119) is a valuable tool for researchers studying EIF2AK1, a protein involved in the regulation of gene expression in response to stress. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to EIF2AK1, researchers can easily detect and analyze this important protein in various cell types.EIF2AK1, also known as PERK, plays a key role in the unfolded protein response pathway, which helps cells cope with endoplasmic reticulum stress. Dysregulation of this pathway has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
By studying EIF2AK1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the EIF2AK1 Polyclonal Antibody (CAB14119) is a valuable tool for researchers interested in studying the role of EIF2AK1 in cellular stress responses and disease pathology. Its high specificity and reactivity make it a reliable choice for Western blotting experiments in the fields of cell biology, molecular biology, and biochemistry.
Product Name:
EIF2AK1 Rabbit Polyclonal Antibody
SKU:
CAB14119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 337-586 of human EIF2AK1 (NP_055228.2).
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using EIF2AK1 Rabbit pAb (CAB14119) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
