The EIF1A Polyclonal Antibody (CAB20954) is a specialized research tool designed for the study of EIF1A, a protein involved in the initiation of protein synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to EIF1A, researchers can detect and analyze this protein in various cell types, making it an ideal tool for studies in molecular biology and cancer research.EIF1A plays a crucial role in the translation initiation process, promoting the binding of the initiator tRNA to the small ribosomal subunit.
Dysregulation of EIF1A expression has been implicated in various diseases, including cancer, making it a valuable target for further investigation. Understanding the function of EIF1A is essential for developing targeted therapies that can effectively modulate protein synthesis in pathological conditions.Overall, the EIF1A Polyclonal Antibody (CAB20954) offers researchers a reliable tool for studying the role of EIF1A in protein synthesis and its potential implications in disease development and progression.
Product Name:
eIF1A Monoclonal Antibody
SKU:
CAB20954
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 65-144 of human eIF1A (P47813).
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA.
Purification Method:
Affinity purification
Gene ID:
1964
Clone Number:
ARC2941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using eIF1A Rabbit mAb (CAB20954) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
