EHMT1 Rabbit Polyclonal Antibody (CAB8513)
- SKU:
- CAB8513
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EHMT1 Rabbit Polyclonal Antibody |
SKU: | CAB8513 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human EHMT1 (NP_079033.4). |
Sequence: | MAAA DAEA VPAR GEPQ QDCC VKTE LLGE ETPM AADE GSAE KQAG EAHM AADG ETNG SCEN SDAS SHAN AAKH TQDS ARVN PQDG TNTL TRIA ENGV SERD SEAA KQNH VTAD DFVQ TSVI GSNG YILN KPAL QAQP LRTT STLA SSLP GHAA KTLP GGAG KGRT PSAF PQTP AAPP ATLG EGSA DTED RKLP APGA DVKV HRAR KTMP KSVV GLHA ASKD PREV REAR DHKE PKEE INKN ISDF GRQQ LLPP FPSL HQSL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GLP; GLP1; KMT1D; KLEFS1; FP13812; EHMT1-IT1; EUHMTASE1; Eu-HMTase1; EHMT1 |
Positive Sample: | MCF7,HeLa,293T(Low expression control) |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 141kDa |
Observed MW: | 180kDa |
The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 79813 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |