The EHHADH Polyclonal Antibody (CAB13488) is a valuable tool for researchers studying EHHADH, an enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, shows high reactivity towards human samples and is validated for use in Western blot applications. By binding specifically to the EHHADH protein, it enables accurate detection and analysis in various cell types, making it ideal for research in metabolic disorders, lipid metabolism, and related pathways.EHHADH plays a crucial role in the breakdown of fatty acids, making it a key player in energy production and metabolic regulation.
Dysregulation of EHHADH has been linked to metabolic disorders such as fatty acid oxidation disorders and lipid storage diseases. By studying the expression and activity of EHHADH using this antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
Product Name:
EHHADH Rabbit Polyclonal Antibody
SKU:
CAB13488
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 444-723 of human EHHADH (NP_001957.2).
The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1962
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using EHHADH Rabbit pAb (CAB13488) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
