The EHD4 Polyclonal Antibody (CAB13766) is specifically designed for research involving EHD4, a protein involved in endocytic recycling processes within cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the EHD4 protein, this antibody allows for the detection and analysis of EHD4 in a variety of cell types, making it an essential tool for studies in cell biology and molecular biology research.EHD4, a member of the EHD family of proteins, plays a crucial role in the regulation of endocytic recycling pathways, impacting processes such as receptor trafficking and membrane dynamics.
Understanding the function of EHD4 is important for unraveling the mechanisms underlying cellular trafficking and signaling, with implications for various physiological and pathological conditions. Research on EHD4 could provide insights into diseases related to endocytic dysfunction, such as neurodegenerative disorders and metabolic syndromes. By shedding light on the roles of EHD4 in cellular processes, this antibody paves the way for advancements in the study of intracellular trafficking mechanisms and the development of targeted therapies.
Product Name:
EHD4 Rabbit Polyclonal Antibody
SKU:
CAB13766
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_644670.1).
Enables cadherin binding activity. Involved in endocytic recycling and protein homooligomerization. Located in endoplasmic reticulum and recycling endosome membrane.
Purification Method:
Affinity purification
Gene ID:
30844
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EHD4 Rabbit pAb (CAB13766) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
