EHD2 Rabbit Polyclonal Antibody (CAB12945)
- SKU:
- CAB12945
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EHD2 Rabbit Polyclonal Antibody |
SKU: | CAB12945 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human EHD2 (NP_055416.2). |
Sequence: | VGTP EVLR VYIG SFWS QPLL VPDN RRLF ELEE QDLF RDIQ GLPR HAAL RKLN DLVK RARL VRVH AYII SYLK KEMP SVFG KENK KKQL ILKL PVIF AKIQ LEHH ISPG DFPD CQKM QELL MAHD FTKF HSLK PKLL EALD EMLT HDIA KLMP LLRQ EELE STEV GVQG GAFE GTHM GPFV ERGP DEAM EDGE EGSD DEAE WVVT KDKS KYDE IFYN LAPA DGKL SGSK AKTW MVGT KLPN SVLG RIWK LSDV DRDG MLDD EEFA LASH LIEA KLEG HGLP ANLP RRLV PPSK RRHK GSAE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 |
Synonyms: | PAST2; EHD2 |
Positive Sample: | A-549,U-87MG,HeLa,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Endosome membrane, Membrane, Peripheral membrane protein, caveola, cytosol. |
Calculated MW: | 61kDa |
Observed MW: | 61kDa |
This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
Purification Method: | Affinity purification |
Gene ID: | 30846 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |