The EHD2 Polyclonal Antibody (CAB12945) is a valuable tool for researchers studying EHD2, a protein involved in intracellular trafficking and membrane recycling processes. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in various research applications, including Western blot and immunofluorescence.EHD2 is essential for the regulation of endocytic pathways and plays a key role in maintaining cellular homeostasis. Dysregulation of EHD2 has been linked to various diseases, including cancer and neurodegenerative disorders.
By targeting EHD2 with this polyclonal antibody, researchers can investigate the protein’s function and its potential role in disease pathogenesis.Overall, the EHD2 Polyclonal Antibody (CAB12945) is a valuable tool for researchers interested in studying the intracellular trafficking mechanisms regulated by EHD2 and its implications in disease. Its specificity and reliability make it an ideal choice for experiments aimed at understanding the cellular processes mediated by EHD2.
Product Name:
EHD2 Rabbit Polyclonal Antibody
SKU:
CAB12945
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human EHD2 (NP_055416.2).
This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
Purification Method:
Affinity purification
Gene ID:
30846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EHD2 Rabbit pAb (CAB12945) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
