The EGR3 Polyclonal Antibody (PAC014371) is an essential tool for researchers studying the EGR3 protein, a transcription factor involved in various cellular processes, including cell growth, differentiation, and response to stress. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for use in immunohistochemistry and Western blotting.EGR3, a member of the early growth response (EGR) family of proteins, functions as a regulator of gene expression in response to extracellular signals, influencing pathways associated with development, tissue repair, and neuronal activity.
Its role in controlling cell fate and behavior makes it a key target for investigations in neuroscience, developmental biology, and cancer research.By targeting EGR3 with this polyclonal antibody, researchers can gain insights into the protein's expression levels and localization in various cell types and tissues, facilitating the study of its impact on physiological and pathological processes. Understanding the regulatory functions of EGR3 can provide valuable information for the development of therapeutic strategies targeting diseases related to its dysregulation.
Antibody Name:
EGR3 Antibody (PACO14371)
Antibody SKU:
PACO14371
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human EGR3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: PACO14371(EGR3 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes.
Background:
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development.
Synonyms:
early growth response 3
NCBI Summary:
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
