The EGR3 Polyclonal Antibody (CAB7669) is a valuable tool for researchers studying EGR3, a transcription factor involved in the regulation of gene expression. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the EGR3 protein, this antibody allows for the detection and analysis of EGR3 in various cell types, aiding in immunology and cancer research studies.EGR3, also known as early growth response protein 3, plays a crucial role in the control of cell growth, differentiation, and response to environmental stimuli.
Its involvement in these processes makes it a key target for research into diseases such as cancer, neurological disorders, and developmental abnormalities. By understanding the function of EGR3, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially develop targeted therapies.
Product Name:
EGR3 Rabbit Polyclonal Antibody
SKU:
CAB7669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EGR3 (NP_004421.2).
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
1960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of SKOV3 cells, using EGR3 antibody (CAB7669) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
